LOGKOW Database Factsheet


The LOGKOW Database eliminates tedious literature searching and reduces the time and cost of obtaining partition coefficient data. A partition or distribution coefficient is the equilibrium ratio of the concentration of a substance dissolved in an organic solvent to the concentration of the same substance dissolved in water. The octanol/water coefficient (logKow) is the standard system which relates to biological activity and the environmental impact of chemicals.

LOGKOW DATABASE contains:
  • over 30,000 critically evaluated octanol/water partition coefficients for over 23,000 organic compounds including many recommended values.
  • over 1,984 current literature references in Chemical Abstracts style.
  • Acid dissociation constants (pKa).
  • Chemicals identified by CAS Registry Number, SMILES notation & molecular formula.
  • Information about the pH, temperature, phases analyzed, nature of the aqueous phase, method and, method reference.

Substances in the database include:
Drugs & pharmaceuticals Environmental hazards
Herbicides, pesticides, fungicides Acid-base addition compounds
Amino-acids & peptides
Dyes, substituted phenols & other wastewater solutes
PCB's (176 congeners), PAH's & other chlorinated compounds
Poisons & toxins

Who should use the LOGKOW DATABASE:
Medicinal ChemistsAnal. ChemistsPharmacologists
Environ. Engineers Chemical EngineersToxicologists
Information Specialists

Professionals in the design of - pharmaceuticals and medicinal chemicals; environmental impact analysis; risk assessment; toxicology; the prediction and correlation of thebioconcentration, soil and sediment absorption of organic pollutants; the solubility and modeling of the environmental fate of organic chemicals - will find this user-friendly databank extremely valuable. LogKow values are used in:

Environmental Analysis Hazard Assessment
Processes where chemico-biological interactions need to be modeled
Drug SynthesisPesticide Design
Extraction procedures


LOGKOW DATABASE is developed and is maintained by Sangster Research Laboratories.

Technical Database Services, Inc.
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